Human growth hormone HGH from algae

Rehovot, Israel-based Rosetta Green Ltd., which specializes in crop improvement for the agriculture and alternative fuel industries using unique genes called microRNAs, has successfully completed an experiment producing human growth hormone (HGH) and validated its biological activity. Proteins produced by both treated and control algae were tested with an in vitro activity test assay by an independent third party using the conventional proliferation method. The activity test assay found that Rosetta Green’s treated algae exhibited hormonal activity.

The project is part of a joint European effort to manufacture chemicals and proteins in algae, which is implemented and funded by the European Union as part of the European Commission’s Seventh Framework Program for Research and Technology Development (FP7). More than ten European organizations are participating in this project, including companies and leading universities, which has an estimated budget of about $7 million US. The project is being managed by Professor Sammy Boussiba of the Microalgal Biotechnology Laboratory of Ben Gurion University of the Negev.
Rosetta Green focuses on using microalgae to develop and produce human proteins for therapeutics, a process that reduces the currently steep drug production costs associated with using mostly mammalian cells and bacteria.

According to Amir Avniel, Rosetta Green’s CEO, “Algae may be an effective source for the production of proteins and vaccines. Rosetta Green has vast experience working with molecular methods in algae. The company worked on the development of designated algae in order to produce the protein in cooperation with the EU. Algae can be used for multiple applications such as producing chemicals, industrial food supplements, bio fuel and food. We believe that the technology that we develop provides significant advantage to improve various traits in plants and algae. We continually seek partners to develop our products and technologies.”

Growth hormone is a peptide hormone secreted by the pituitary gland. Among its functions are the regulation of protein production and the stimulation of bone growth in children. Growth hormone is normally secreted throughout a person’s life, but the amount decreases by 14% every decade after the age of 21. A deficiency in this hormone is known to cause growth block, short stature and dwarfism.

Currently, growth hormone is produced by major multi-nationals such as Pfizer, Lilly, and Merck Serono and used as a prescription medicine to treat children with growth problems and adults with hormone deficiency as well as other symptoms characterized by growth complications. Total annual sales of human growth hormone are estimated at approximately $3 Billion US.

Growth hormone is administered today primarily through daily injections over several years. The accumulated cost can reach hundreds of thousands of dollars per child. Rosetta Green believes that manufacturing the hormone using microalgae will likely reduce today’s high cost of production, which relies upon currently available techniques. 

More info at http://www.rosettagreen.com/.

CCRES special thanks to Professor Sammy Boussiba of the Microalgal Biotechnology Laboratory of Ben Gurion University of the Negev.

CCRES ALGAE Project 

part of 

Croatian Center of Renewable Energy Sources (CCRES)

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CCRES ALTERNATIVE ENERGY

 

CROATIAN CENTER of RENEWABLE ENERGY SOURCES

 (CCRES)

Alternative Energy

 

Energy has become integral parts of our day-to-day lives. Energy is required to produce electricity for domestic and industrial applications. We need energy to drive our vehicles, to run the machines, keep our houses cool and hot, run the computers and mobiles, and for a number of other purposes.

Comparison of Traditional and Alternative Energy Sources:

Traditionally we have been using fossil fuels for production of electric power and driving our vehicles. The fuels used for the generation of electric power are fossil fuels like coal and oil, and nuclear fuels like uranium. The fuels used commonly for running the vehicles are crude oils like gasoline and diesel. Alternative energy refers to the energy that is not dependent on fossil fuels, crude oil and nuclear fuels. Alternative energy, also called as renewable energy, is obtained from various sources like radiations of the sun (solar energy), wind, water, geothermal heat and tides in the oceans. Burning of fossil fuels is one of the major causes of environmental pollution and greenhouse effect. They release lots of carbon dioxide and particulate matter. The alternative or renewable energy is considered to be the clean energy since extracting energy from its sources does not produce any pollution.

The sources of energy like fossil fuels, crude oil and nuclear fuels are also called as non-renewable sources of energy since their deposits are reducing in the nature as they are being used extensively throughout the world. Fuels like coal, natural gas and oil took millions of years to develop but once used they cannot be replaced immediately. The alternative energy on the other hand is available in abundance from various sources and they get replaced easily immediately or within short period of time.

Alternative sources of energy provide unending supply of energy. For instance the solar energy from the sun will be available for unlimited period of time till the sun keeps shining. Solar energy can be collected by the collectors and it can be used for a number of applications like cooking food, heating water, generating electricity, running the vehicles etc. Similarly, the wind will keep on blowing on the surface of the earth tills its atmosphere is in place so it can be utilized for unlimited period of time. The ability of the wind to produce motion can be utilized to run the fans of the windmill and produce electricity from them.

The tidal energy is obtained from waves of the oceans having huge quantity of water that would last forever. One of the important sources of alternative energy is hydro-power used for the generation of electricity in hydroelectric power plants. Throughout the world, the hydroelectric power plants are one of the major sources for the generation of electricity. In these plants the flow of river is blocked at certain places and water is allowed to be collected at large height in the dam. The rivers have been flowing since thousands of years and continue to exist for unlimited period of time as they are replenished by rain water from time-to-time.

Geothermal energy is obtained from the lower layers of the earth usually for producing the heating effect. Once the energy is obtained from the earth, it is replaced immediately naturally and it can be used for ending period of time interval.

Another important source of alternative energy is the biomass like waste wood, leaves of the plants, broken branches and twigs of the trees, agricultural wastes, garbage, human wastes etc. The fuels obtained from biomass are called bio-fuels. Some of the common bio-fuels are ethanol, biodiesel, and natural gas. Biodiesel is a type of alternative fuel used for running of the vehicles. It is made from renewable energy sources like plant and animal fats. Biodiesel is not a petroleum fuel, but it can be easily blended with petroleum fuel diesel in various proportions.

All the above alternative sources of energy are expected to last for long intervals of time line. While the supply of coal, oil and natural gas is expected to reduce and stop in the future, the supply of energy from sources like sun, wind, water, earth, and biomass is expected to last forever.

Consumption of alternative energy in US has been increasing over the years. In the year 2009 the consumption of alternative energy in US was 7.7 quadrillion Btu, which was 8% of all the energy used in the whole nation. Half of the alternative energy was used for producing electricity, while 10% of the total electricity produced was from alternative energy sources. Besides this alternative energy sources were also used for production of heat and steam. Alternative energy was also used for transportation, and to provide heat for homes and businesses.

Alternative energy sources reduce the pressure on fossil fuels and also help keep environment clean. The only major problem is that alternative energy is expensive compared to the fossil fuels mainly because they are located in remote places and its difficult to bring them to the main grid. Some of the sources like wind and solar are not uniform during various periods of the day and the year. However, their demand has been increasing and various technologies are being developed to utilize alternative energy sources more efficiently.

CCRES 

special thanks to   

Escapeartist, Inc

 CROATIAN CENTER of RENEWABLE ENERGY SOURCES 

(CCRES)

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